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Figure 1 summarizes the hour pharmacokinetic profile of testosterone for patients maintained on Testim 50 mg or Testim mg for 30 days. Figure 2 summarizes the hour pharmacokinetic profile of DHT for patients maintained on Testim 50 mg or Testim mg for 30 days. The effect of showering with mild soap at 1, 2 and 6 hours post application of Testim mg was evaluated in a clinical trial in 12 men. The study demonstrated that the overall effect of washing was to lessen testosterone levels; however, when washing occurred two or more hours post drug application, serum testosterone levels remained within Buying legal Nolvadex online in UK normal range. Circulating testosterone is chiefly bound in Buying legal Nolvadex online in UK serum to sex hormone-binding globulin SHBG and albumin. The albumin-bound fraction of testosterone easily dissociates from albumin and is presumed to be natural buying methandienone online in uk
">bioactive. The portion of testosterone bound to SHBG is not considered biologically active. The amount of SHBG in the serum and the total testosterone level will determine the distribution of bioactive and nonbioactive androgen. There is considerable variation in the half-life of testosterone as reported in the literature, ranging from ten to minutes. Testosterone is metabolized to various keto steroids through two different pathways. The major active metabolites of testosterone are estradiol and DHT.

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